My friend Deena Spear, one of the great healers I know, recently put me in touch with a man who nearly died from a prescribed Fluoroquinolone drug for a urinary tract infection. He had one of the life-threatening “side effects,” especially common with Levaquin and Tequin.

Incidentally, a couple of years ago, within a few days on one of those drugs, I rapidly developed severe hypoglycemia, which took me a year to overcome. Indeed those drugs can CAUSE diabetes as well as severe polyneuropathy and many other serious problems.

I have had some correspondence with the gentleman and learned that he has mostly recovered, using calcium D-glucarate.

Glucaric acid is found in small quantities in oranges, apples, grapefruit, cherries, and cruciferous vegetables.

The calcium salt of this natural substance inhibits beta-glucuronidase, an enzyme produced in the colon by bacteria there. Elevated beta-glucuronidase activity is associated with a significantly increased risk of breast, prostate, and colon cancers, 3 of the most common! Interestingly, calcium-D-glucarate also helps regulate estrogen metabolism and lower cholesterol. Thus, gynecomastia reversal in older men, who have impaired regulation of estrogen, is a potential benefit from calcium-D-glucarate (DCG).

Perhaps most importantly, DCG is a major detoxifier of various chemical carcinogens, steroids, and lipid-soluble toxins. It increases excretion of xenobiotic compounds — those foreign substances such as antibiotics, pollutants, dioxin and polychlorinated biphenyl’s, etc. It also enhances intestinal-hepatic circulation. DCG may also be helpful to athletes doing intensive bodybuilding, in ridding them of the toxins associated with their metabolism.

Calcium D Glucarate Side Effects

Calcium D Glucarate is reportedly used to detoxify the body and to prevent and treat cancer. Studies on lab animals noted that calcium glucarate helps speed up the process of releasing the body of carcinogens. Other studies in rats noted that calcium glucarate can slow the development of tumors and reduce their number exposed to carcinogens. However, not much research or studies have been done on humans to note the same benefits. 

Due to the lack of studies on humans and Calcium D Glucarate intake, it is advised that pregnant women refrain from using Calcium D Glucarate supplements unless under a doctor’s approval or supervision. It is also advised not to mix Calcium D Glucarate supplementation and other medications. Calcium D Glucarate may decrease effectiveness of certain cholesterol and pain relieving medication. Last but not least, Calcium D Glucarate may also temporarily affect hormone levels.


Gynecomastia, also known as enlarged male breast tissue, is a condition where there is an imbalance of testosterone and estrogen hormones. The swelling of male breast tissue can also be a side effect of certain medications and/or diseases. Gynecomastia can be an issue for males of all ages but mostly affects those during the newborn period.

Men’s bodies typically have small amounts of estrogen, the hormone which controls breast growth. However, if the male body produces too much estrogen, or have low levels of testosterone- their breasts may enlarge. Those who are obese can also have enlarged breasts.

Considering the pollution of the world with petrochemical pollutants and artificial estrogens, etc, it appears everyone may benefit from calcium D-glucarate. If you have had antibiotics and have never felt “right” since then, consider taking calcium-D-Glucarate.

The general dose for an adult is 250 mg twice daily. It contains 50 mg of calcium so you receive the recommended 200 mg of D-glucarate. This small amount of calcium is not of concern in those taking large dosages of D 3. In fact, it is less calcium than in a good multivitamin/mineral supplement. It is available at or 888-242-6105.


Biochem Med Metab Biol 1990;43:83-92.
Cancer Detect Prev 1997;21:178-190.
Isr J Med Sci 1995;31:101-105.

Norman Shealy, M.D., Ph.D. is the father of holistic medicine. He recommends autogenic focus (the basis of the Biogenics System) as part of your overall commitment to self-health. Register to download your FREE autogenic focus MP3 now.

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